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Deadlock Bible
Matchup · November 6, 2026

Vyper vs Sinclair

51.3%
Even13,483 matches
All Vyper matchups & counters

Updated · Patch Nov 4, 2026

Deadlock Bible take

How Vyper beats Sinclair

Assassin vs Mystic

Mystics are often fragile without their spells. Dive them right after they cast.

Your game plan as Vyper

A slippery gunner who slides into your backline with a dagger and a bola.

Lane
Screwjab Dagger stacks damage and slow. Slither makes you faster than anyone.
Mid game
Lethal Venom gets stronger as targets lose health, so save it to finish fights.
Late game
Petrifying Bola petrifies on direct hit. Land it, then shoot.

How to beat Sinclair

A magician who borrows your best trick and uses it on you.

  • 01Bait the copy: use your weakest ultimate first.
  • 02Kill the Assistant.
  • 03Rabbit Hex is area-targeted, so you can walk out of it.
Per match

Head-to-head

VyperSinclair
51.3%Win rate48.7%
0.99Kills per death0.88
+11.7Last-hit edge+0
+0.9Deny edge+0
+960Soul lead+0
+4.7KObjective damage edge+0
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Laning

Win the lane: Vyper into Sinclair

  1. 01Vyper out-farms Sinclair by ~11.7 last hits per match. Contest every orb and punish them for walking up to last-hit.
  2. 02Sinclair deals most damage with abilities. Trade right after they’ve used their main spell, and consider early Spirit Shielding.
Skill order

Skill order for this matchup

52.3% win rate over 34,267 matches

  • Max first

    You out-farm Sinclair: keep the standard order and push your lead with Slither.

Sinclair’s kit

Threats

Sinclair has no hard crowd control — take the trades.

Vyper’s kit

Your tools

Lethal Venom
Stun28s cd
Petrifying BolaUltimate
StunSlow115s cd
Screwjab Dagger
Slow10s cd
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Mid & late game

Winning the fights after lane

  • Vyper averages 0.99 kills per death against Sinclair.
  • On average Vyper finishes 960 souls ahead of Sinclair — convert the lead into objectives.
  • Vyper deals 4.7k more objective damage per match than Sinclair — push structures when you win lane.
  • Track Audience Participation (85s cooldown). The window right after Sinclair uses it is your best time to fight.
Also check

Who else beats Sinclair

GravesFavouredGraves vs Sinclair61.7%40,677 matchesPaigeFavouredPaige vs Sinclair60.3%27,931 matchesRat KingFavouredRat King vs Sinclair60.2%50,438 matchesKelvinFavouredKelvin vs Sinclair60.0%12,495 matches
FAQ

Matchup questions

Who wins Vyper vs Sinclair?

Vyper wins 51.3% of 13,483 recent matches against Sinclair — even.

How do I beat Sinclair as Vyper?

Vyper out-farms Sinclair by ~11.7 last hits per match. Contest every orb and punish them for walking up to last-hit. Track Audience Participation (85s cooldown). The window right after Sinclair uses it is your best time to fight.

What should Vyper buy against Sinclair?

Spirit Shielding, Spirit Resilience.