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Deadlock Bible
Matchup · November 6, 2026

Sinclair vs Vyper

48.7%
Even13,483 matches
All Sinclair matchups & counters

Updated · Patch Nov 4, 2026

Deadlock Bible take

How Sinclair beats Vyper

Mystic vs Assassin

Keep your CC for their dive. One stun on an assassin is usually a kill for your team.

Your game plan as Sinclair

A magician who borrows your best trick and uses it on you.

Lane
Vexing Bolt grows with distance; Spectral Assistant doubles your attacks.
Mid game
Rabbit Hex turns enemies into rabbits who take more damage.
Late game
Audience Participation copies an enemy ultimate. Copy the strongest one on their team.

How to beat Vyper

A slippery gunner who slides into your backline with a dagger and a bola.

  • 01Stay above half health; Lethal Venom scales with missing health.
  • 02Dodge Petrifying Bola’s direct hit.
  • 03CC her before she slides away.
Per match

Head-to-head

SinclairVyper
48.7%Win rate51.3%
0.88Kills per death0.99
+0Last-hit edge+11.7
+0Deny edge+0.9
+0Soul lead+960
+0Objective damage edge+4.7K
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Laning

Win the lane: Sinclair into Vyper

  1. 01Vyper wins the farm by ~11.7 last hits per match. Prioritise safe last hits and denies over trades, and let your lane partner zone.
  2. 02Vyper looks for burst windows. Don’t sit in lane at low health, and ping the moment they disappear — they’re hunting.
Skill order

Skill order for this matchup

49.9% win rate over 12,565 matches

  • Early point

    Vyper wins the farm: an early point into Vexing Bolt clears waves and keeps you in lane.

Vyper’s kit

Threats

Lethal Venom
Stun28s cd
Petrifying BolaUltimate
StunSlow115s cd
Screwjab Dagger
Slow10s cd
Sinclair’s kit

Your tools

Your gun and your items carry this one.

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Mid & late game

Winning the fights after lane

  • Sinclair averages 0.88 kills per death against Vyper.
  • Sinclair finishes 960 souls behind Vyper on average — play for teamfights and scaling rather than lane kills.
  • Sinclair deals 4.7k less objective damage per match than Vyper — let teammates take structures while you hold.
  • Track Petrifying Bola (115s cooldown). The window right after Vyper uses it is your best time to fight.
Also check

Who else beats Vyper

GravesFavouredGraves vs Vyper62.0%53,158 matchesPaigeFavouredPaige vs Vyper59.8%41,897 matchesSevenFavouredSeven vs Vyper58.4%47,696 matchesRat KingFavouredRat King vs Vyper58.4%71,848 matches
FAQ

Matchup questions

Who wins Sinclair vs Vyper?

Sinclair wins 48.7% of 13,483 recent matches against Vyper — even.

How do I beat Vyper as Sinclair?

Vyper wins the farm by ~11.7 last hits per match. Prioritise safe last hits and denies over trades, and let your lane partner zone. Track Petrifying Bola (115s cooldown). The window right after Vyper uses it is your best time to fight.

What should Sinclair buy against Vyper?

Debuff Reducer, Unstoppable, Weapon Shielding.