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Deadlock Bible
Matchup · November 6, 2026

Vyper vs Nurse Harrow

45.7%
Unfavoured34,331 matches
All Vyper matchups & counters

Updated · Patch Nov 4, 2026

Deadlock Bible take

How Vyper beats Nurse Harrow

Your game plan as Vyper

A slippery gunner who slides into your backline with a dagger and a bola.

Lane
Screwjab Dagger stacks damage and slow. Slither makes you faster than anyone.
Mid game
Lethal Venom gets stronger as targets lose health, so save it to finish fights.
Late game
Petrifying Bola petrifies on direct hit. Land it, then shoot.

How to beat Nurse Harrow

A battlefield medic who heals with her gun, starves enemy buffs with leeches and terrifies anyone who looks her in the eye.

  • 01Turn your back to Lurking Terrors: facing away halves its damage and stops the terror building.
  • 02Burst the Wretched Vapors target after the rush ends; the delayed damage lands all at once unless she heals it.
  • 03Pressure Harrow while Healing Needles is loaded; her clip is healing allies, not shooting you.
Punish
Per match

Head-to-head

VyperNurse Harrow
45.7%Win rate54.3%
0.91Kills per death0.66
+21.6Last-hit edge+0
+0.4Deny edge+0
+2.5KSoul lead+0
+7.1KObjective damage edge+0
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Laning

Win the lane: Vyper into Nurse Harrow

  1. 01Vyper out-farms Nurse Harrow by ~21.6 last hits per match. Contest every orb and punish them for walking up to last-hit.
  2. 02Nurse Harrow has sustain (Healing Needles). Short, sharp trades beat long ones — buy anti-heal early.
Skill order

Skill order for this matchup

This matchup
Usual

52.3% win rate over 34,267 matches

Nurse Harrow’s kit

Threats

Wretched Vapors
Slow40s cd
Healing Needles
Slow
Vyper’s kit

Your tools

Lethal Venom
Stun28s cd
Petrifying BolaUltimate
StunSlow115s cd
Screwjab Dagger
Slow10s cd
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Mid & late game

Winning the fights after lane

  • Vyper averages 0.91 kills per death against Nurse Harrow.
  • On average Vyper finishes 2.5k souls ahead of Nurse Harrow — convert the lead into objectives.
  • Vyper deals 7.1k more objective damage per match than Nurse Harrow — push structures when you win lane.
  • Track Lurking Terrors (200s cooldown). The window right after Nurse Harrow uses it is your best time to fight.
Also check

Who else beats Nurse Harrow

GravesFavouredGraves vs Nurse Harrow55.0%113,742 matchesBabaFavouredBaba vs Nurse Harrow53.9%40,972 matchesPaigeFavouredPaige vs Nurse Harrow53.9%92,925 matchesRat KingFavouredRat King vs Nurse Harrow53.3%175,718 matches
FAQ

Matchup questions

Who wins Vyper vs Nurse Harrow?

Vyper wins 45.7% of 34,331 recent matches against Nurse Harrow — unfavoured.

How do I beat Nurse Harrow as Vyper?

Vyper out-farms Nurse Harrow by ~21.6 last hits per match. Contest every orb and punish them for walking up to last-hit. Track Lurking Terrors (200s cooldown). The window right after Nurse Harrow uses it is your best time to fight.

What should Vyper buy against Nurse Harrow?

Toxic Bullets, Healbane.