Nurse Harrow vs Vyper
Updated · Patch Nov 4, 2026
How Nurse Harrow beats Vyper
Your game plan as Nurse Harrow
A battlefield medic who heals with her gun, starves enemy buffs with leeches and terrifies anyone who looks her in the eye.
How to beat Vyper
A slippery gunner who slides into your backline with a dagger and a bola.
- 01Stay above half health; Lethal Venom scales with missing health.
- 02Dodge Petrifying Bola’s direct hit.
- 03CC her before she slides away.
Head-to-head
Win the lane: Nurse Harrow into Vyper
- 01Vyper wins the farm by ~21.6 last hits per match. Prioritise safe last hits and denies over trades, and let your lane partner zone.
- 02Vyper looks for burst windows. Don’t sit in lane at low health, and ping the moment they disappear — they’re hunting.
- 03Your own sustain (Healing Needles) wins extended lanes — stay longer than they can.
Skill order for this matchup



60% win rate over 90,585 matches
Early pointPut an early point into Healing Needles: Vyper dives on you, and an escape ready beats a lost trade.
HoldHold Healing Needles for Petrifying Bola — use it the moment Vyper commits, not before.
Early pointVyper wins the farm: an early point into Leech Therapy clears waves and keeps you in lane.
Threats



Your tools


Winning the fights after lane
- Nurse Harrow averages 0.66 kills per death against Vyper.
- Nurse Harrow finishes 2.5k souls behind Vyper on average — play for teamfights and scaling rather than lane kills.
- Nurse Harrow deals 7.1k less objective damage per match than Vyper — let teammates take structures while you hold.
- Track Petrifying Bola (115s cooldown). The window right after Vyper uses it is your best time to fight.
Who else beats Vyper




Matchup questions
Who wins Nurse Harrow vs Vyper?
Nurse Harrow wins 54.3% of 34,331 recent matches against Vyper — favoured.
How do I beat Vyper as Nurse Harrow?
Vyper wins the farm by ~21.6 last hits per match. Prioritise safe last hits and denies over trades, and let your lane partner zone. Track Petrifying Bola (115s cooldown). The window right after Vyper uses it is your best time to fight.

