Matchup · November 6, 2026
Vyper vs Infernus
46.6%
Unfavoured50,054 matches
All Vyper matchups & countersUpdated · Patch Nov 4, 2026
Deadlock Bible take
How Vyper beats Infernus
Assassin vs Mystic
Mystics are often fragile without their spells. Dive them right after they cast.
Your game plan as Vyper
A slippery gunner who slides into your backline with a dagger and a bola.
Lane
Screwjab Dagger stacks damage and slow. Slither makes you faster than anyone.
Mid game
Lethal Venom gets stronger as targets lose health, so save it to finish fights.
Late game
Petrifying Bola petrifies on direct hit. Land it, then shoot.
How to beat Infernus
A pyromaniac who wins by keeping everyone burning for just a bit too long.
- 01Short trades. Afterburn punishes long ones.
- 02Concussive Combustion can’t be interrupted — walk out of it.
- 03Buy anti-heal and Spirit Resist; most of his damage is spirit.
Respect
Punish
After Flame Dash is spent
Per match
Head-to-head
VyperInfernus
46.6%Win rate53.4%
0.92Kills per death1.13
+0Last-hit edge+14.5
+0.4Deny edge+0
+0Soul lead+1.3K
+2.1KObjective damage edge+0
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Laning
Win the lane: Vyper into Infernus
- 01Infernus wins the farm by ~14.5 last hits per match. Prioritise safe last hits and denies over trades, and let your lane partner zone.
- 02Infernus deals most damage with abilities. Trade right after they’ve used their main spell, and consider early Spirit Shielding.
Skill order
Skill order for this matchup
This matchup
Usual
52.3% win rate over 34,267 matches
Early pointInfernus wins the farm: an early point into Screwjab Dagger clears waves and keeps you in lane.
Infernus’s kit
Threats
Concussive CombustionUltimate
Stun190s cd
Napalm
Slow25s cd
Flame Dash
Slow38s cd
Vyper’s kit
Your tools
Lethal Venom
Stun28s cd
Petrifying BolaUltimate
StunSlow115s cd
Screwjab Dagger
Slow10s cd
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Mid & late game
Winning the fights after lane
- Vyper averages 0.92 kills per death against Infernus.
- Vyper finishes 1.3k souls behind Infernus on average — play for teamfights and scaling rather than lane kills.
- Vyper deals 2.1k more objective damage per match than Infernus — push structures when you win lane.
- Track Concussive Combustion (190s cooldown). The window right after Infernus uses it is your best time to fight.
Also check
Who else beats Infernus
FAQ
Matchup questions
Who wins Vyper vs Infernus?
Vyper wins 46.6% of 50,054 recent matches against Infernus — unfavoured.
How do I beat Infernus as Vyper?
Infernus wins the farm by ~14.5 last hits per match. Prioritise safe last hits and denies over trades, and let your lane partner zone. Track Concussive Combustion (190s cooldown). The window right after Infernus uses it is your best time to fight.