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Deadlock Bible
Matchup · November 6, 2026

Infernus vs Vyper

53.4%
Favoured50,054 matches
All Infernus matchups & counters

Updated · Patch Nov 4, 2026

Deadlock Bible take

How Infernus beats Vyper

Mystic vs Assassin

Keep your CC for their dive. One stun on an assassin is usually a kill for your team.

Your game plan as Infernus

A pyromaniac who wins by keeping everyone burning for just a bit too long.

Lane
Every bullet stacks Afterburn. Open trades with Napalm; it amplifies your damage on whoever it hits.
Mid game
Flame Dash through fights and leave fire behind you. Long, messy skirmishes are where you win.
Late game
Concussive Combustion can’t be interrupted once you start it. Flame Dash into the middle of their team and blow up.

How to beat Vyper

A slippery gunner who slides into your backline with a dagger and a bola.

  • 01Stay above half health; Lethal Venom scales with missing health.
  • 02Dodge Petrifying Bola’s direct hit.
  • 03CC her before she slides away.
Per match

Head-to-head

InfernusVyper
53.4%Win rate46.6%
1.13Kills per death0.92
+14.5Last-hit edge+0
+0Deny edge+0.4
+1.3KSoul lead+0
+0Objective damage edge+2.1K
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Laning

Win the lane: Infernus into Vyper

  1. 01Infernus out-farms Vyper by ~14.5 last hits per match. Contest every orb and punish them for walking up to last-hit.
  2. 02Vyper looks for burst windows. Don’t sit in lane at low health, and ping the moment they disappear — they’re hunting.
Skill order

Skill order for this matchup

This matchup
Usual

51.2% win rate over 136,069 matches

Vyper’s kit

Threats

Lethal Venom
Stun28s cd
Petrifying BolaUltimate
StunSlow115s cd
Screwjab Dagger
Slow10s cd
Infernus’s kit

Your tools

Concussive CombustionUltimate
Stun190s cd
Napalm
Slow25s cd
Flame Dash
SlowMobility38s cd
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Mid & late game

Winning the fights after lane

  • Infernus averages 1.13 kills per death against Vyper.
  • On average Infernus finishes 1.3k souls ahead of Vyper — convert the lead into objectives.
  • Infernus deals 2.1k less objective damage per match than Vyper — let teammates take structures while you hold.
  • Track Petrifying Bola (115s cooldown). The window right after Vyper uses it is your best time to fight.
Also check

Who else beats Vyper

GravesFavouredGraves vs Vyper62.0%53,158 matchesPaigeFavouredPaige vs Vyper59.8%41,897 matchesSevenFavouredSeven vs Vyper58.4%47,696 matchesRat KingFavouredRat King vs Vyper58.4%71,848 matches
FAQ

Matchup questions

Who wins Infernus vs Vyper?

Infernus wins 53.4% of 50,054 recent matches against Vyper — favoured.

How do I beat Vyper as Infernus?

Infernus out-farms Vyper by ~14.5 last hits per match. Contest every orb and punish them for walking up to last-hit. Track Petrifying Bola (115s cooldown). The window right after Vyper uses it is your best time to fight.

What should Infernus buy against Vyper?

Debuff Reducer, Unstoppable, Weapon Shielding.