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Deadlock Bible
Matchup · November 6, 2026

Vyper vs McGinnis

46.6%
Unfavoured19,121 matches
All Vyper matchups & counters

Updated · Patch Nov 4, 2026

Deadlock Bible take

How Vyper beats McGinnis

Assassin vs Mystic

Mystics are often fragile without their spells. Dive them right after they cast.

Your game plan as Vyper

A slippery gunner who slides into your backline with a dagger and a bola.

Lane
Screwjab Dagger stacks damage and slow. Slither makes you faster than anyone.
Mid game
Lethal Venom gets stronger as targets lose health, so save it to finish fights.
Late game
Petrifying Bola petrifies on direct hit. Land it, then shoot.

How to beat McGinnis

The engineer. McGinnis wins by making the battlefield hers before the fight.

  • 01Destroy turrets before fighting near them.
  • 02Walk around Spectral Wall’s edge rather than through it.
  • 03Dive her; she’s slow while casting Heavy Barrage.
Punish
Per match

Head-to-head

VyperMcGinnis
46.6%Win rate53.4%
0.93Kills per death0.83
+0Last-hit edge+5.7
+0Deny edge+2.9
+828Soul lead+0
+2.8KObjective damage edge+0
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Laning

Win the lane: Vyper into McGinnis

  1. 01McGinnis wins the farm by ~5.7 last hits per match. Prioritise safe last hits and denies over trades, and let your lane partner zone.
  2. 02McGinnis denies ~2.9 more orbs per match — secure your orbs before they can.
  3. 03McGinnis deals most damage with abilities. Trade right after they’ve used their main spell, and consider early Spirit Shielding.
Skill order

Skill order for this matchup

This matchup
Usual

52.3% win rate over 34,267 matches

McGinnis’s kit

Threats

Spectral Wall
Slow50s cd
Heavy BarrageUltimate
Slow200s cd
Vyper’s kit

Your tools

Lethal Venom
Stun28s cd
Petrifying BolaUltimate
StunSlow115s cd
Screwjab Dagger
Slow10s cd
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Mid & late game

Winning the fights after lane

  • Vyper averages 0.93 kills per death against McGinnis.
  • On average Vyper finishes 828 souls ahead of McGinnis — convert the lead into objectives.
  • Vyper deals 2.8k more objective damage per match than McGinnis — push structures when you win lane.
  • Track Heavy Barrage (200s cooldown). The window right after McGinnis uses it is your best time to fight.
Also check

Who else beats McGinnis

PaigeFavouredPaige vs McGinnis58.1%44,192 matchesRat KingFavouredRat King vs McGinnis57.9%67,297 matchesSevenFavouredSeven vs McGinnis57.6%42,360 matchesVictorFavouredVictor vs McGinnis55.9%38,368 matches
FAQ

Matchup questions

Who wins Vyper vs McGinnis?

Vyper wins 46.6% of 19,121 recent matches against McGinnis — unfavoured.

How do I beat McGinnis as Vyper?

McGinnis wins the farm by ~5.7 last hits per match. Prioritise safe last hits and denies over trades, and let your lane partner zone. Track Heavy Barrage (200s cooldown). The window right after McGinnis uses it is your best time to fight.

What should Vyper buy against McGinnis?

Spirit Shielding, Spirit Resilience.