Nurse Harrow vs Infernus
Updated · Patch Nov 4, 2026
How Nurse Harrow beats Infernus
Your game plan as Nurse Harrow
A battlefield medic who heals with her gun, starves enemy buffs with leeches and terrifies anyone who looks her in the eye.
How to beat Infernus
A pyromaniac who wins by keeping everyone burning for just a bit too long.
- 01Short trades. Afterburn punishes long ones.
- 02Concussive Combustion can’t be interrupted — walk out of it.
- 03Buy anti-heal and Spirit Resist; most of his damage is spirit.
Head-to-head
Win the lane: Nurse Harrow into Infernus
- 01Infernus wins the farm by ~37.8 last hits per match. Prioritise safe last hits and denies over trades, and let your lane partner zone.
- 02Infernus deals most damage with abilities. Trade right after they’ve used their main spell, and consider early Spirit Shielding.
- 03Your own sustain (Healing Needles) wins extended lanes — stay longer than they can.
Skill order for this matchup



60% win rate over 90,585 matches
HoldHold Healing Needles for Concussive Combustion — use it the moment Infernus commits, not before.
Early pointInfernus wins the farm: an early point into Leech Therapy clears waves and keeps you in lane.
Threats



Your tools


Winning the fights after lane
- Nurse Harrow averages 0.60 kills per death against Infernus.
- Nurse Harrow finishes 3.6k souls behind Infernus on average — play for teamfights and scaling rather than lane kills.
- Nurse Harrow deals 4.6k less objective damage per match than Infernus — let teammates take structures while you hold.
- Track Concussive Combustion (190s cooldown). The window right after Infernus uses it is your best time to fight.
Who else beats Infernus




Matchup questions
Who wins Nurse Harrow vs Infernus?
Nurse Harrow wins 51.7% of 90,436 recent matches against Infernus — even.
How do I beat Infernus as Nurse Harrow?
Infernus wins the farm by ~37.8 last hits per match. Prioritise safe last hits and denies over trades, and let your lane partner zone. Track Concussive Combustion (190s cooldown). The window right after Infernus uses it is your best time to fight.

